By studying bacterial growth and division in habitat landscapes consisting of nano-scale constrictions we select for phenotypes with new characteristics. These phenotypes exhibit novel patterns of morphology as well as cell-division mechanics and physiological regulation.
By studying intracellular networks (Cytoskeletal proteins, cell-wall assembly and regulation, and Chromosome dynamics we challenge current theoretical models of cell division and chromosome segregation. We aim to develop new theoretical frameworks leveraging our in house-experiments.
The goal is to unify cell-wall assembly models, with cell-cycle & cell-division regulation models with theory of molecular autopoiesis. The theoretical framework develop here goes hand on hand with our experimental biophysics program on Adaptation